Nucleotide sequence analyses of the MRP 1 gene in four populations suggest negative selection on its coding region

Table 3 Frequencies of insertion/deletions (indel) identified at MRP 1

No.	indel ID	Region	Amino acid change	dbSNP (rs)	Population	n	frequency (%)
							insertion	Deletion
Indel1	5'UTR/-74 14bp indel	5'UTR	-	-	CH	36	100.00	0.00
					ML	35	100.00	0.00
					IN	35	97.14	2.86
					CAU	36	100.00	0.00
Indel2	I2/17 G indel	Intron 2	-	-	CH	36	0.00	100.00
					ML	35	0.00	100.00
					IN	35	0.00	100.00
					CAU	36	1.39	98.61
Indel3	I3/-70 T indel	Intron 3	-	-	CH	36	0.00	100.00
					ML	35	0.00	100.00
					IN	35	0.00	100.00
					CAU	36	1.39	98.61
Indel4	I5/-25 12 bp indel	Intron 5	-	rs3830390	CH	36	0.00	100.00
					ML	35	0.00	100.00
					IN	35	1.43	98.57
					CAU	36	0.00	100.00
Indel5	I12/-119 G indel	Intron 12	-	-	CH	36	0.00	100.00
					ML	35	1.43	98.57
					IN	35	0.00	100.00
					CAU	36	0.00	100.00
Indel6	I16/7 6bp indel	Intron 16	-	-	CH	36	0.00	100.00
					ML	35	1.43	98.57
					IN	35	0.00	100.00
					CAU	36	0.00	100.00
Indel7	I17/-182 5bp indel	Intron 17	-	-	CH	30	81.70	18.30
					ML	35	74.29	25.71
					IN	29	86.20	13.80
					CAU	30	80.00	20.00
Indel8	I18/-38 AT indel	Intron 18	-	-	CH	36	0.00	100.00
					ML	35	2.86	97.14
					IN	35	0.00	100.00
					CAU	36	1.39	98.61
Indel9	I24/49 C indel	Intron 24	-	-	CH	36	0.00	100.00
					ML	35	0.00	100.00
					IN	35	1.43	98.57
					CAU	36	0.00	100.00
Indel10	I29/-13 T indel	Intron 29	-	rs4148379	CH	36	45.83	54.17
					ML	35	41.43	58.57
					IN	35	61.43	38.57
					CAU	36	75.00	25.00

ISSN: 1471-2164