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Table 2 Genes that showed significant alterations (q ≤ 5%) in brains of scrapie-infected mice at 104 dpi

From: Gene expression alterations in brains of mice infected with three strains of scrapie

Scan

Clone ID

Name

SAM Score(d)

q-value (%)

Ave. FC

L

AI848245

beta-2 microglobulin*

2.0

4.2

1.3

L

AI836786

complement component 1 q alpha*

2.1

4.2

1.3

L

AI835314

cyclin-dependent kinase 5, regulatory subunit (p35)

1.9

4.2

1.3

L

AI851280

docking protein 4

1.8

4.2

1.2

L

AI854785

endogenous retrovirus, Intracisternal A particles

1.8

4.2

1.2

L

SSHI-2f6

endogenous retrovirus truncated gag

1.8

4.2

1.4

L

AI841933

eukaryotic translation initiation factor 3, subunit 2 (beta)

1.8

4.2

1.2

L

AI836096

glial fibrillary acidic protein

3.7

4.2

1.9

L

AI854206

hexosaminidase B*

2.0

4.2

1.3

L

AI848012

kinesin family member 3A

1.9

4.2

1.3

L

AI842053

lectin, galactoside-binding, soluble, 3 binding protein*

1.9

4.2

1.2

L

AI849127

unknown EST

2.0

4.2

1.3

L

AI854905

unknown EST

1.9

4.2

1.3

L

AI853719

unknown EST

1.8

4.2

1.3

L

SSHII-1h12

not sequenced

1.8

4.2

1.2

L

AI840066

Immunoglobulin superfamily, member 4B*

1.9

4.2

1.3

L

AI849299

Protein tyrosine phosphatase, receptor type Z, polypeptide 1

1.8

4.2

1.2

L

AI851594

RIKEN cDNA 1300010M03 gene

1.8

4.2

1.2

L

AI850724

RIKEN cDNA 2400003C14 gene

2.3

4.2

1.3

L

AI843193

RIKEN cDNA E130114P18 gene

2.2

4.2

1.3

L

AI840441

secretogranin III*

1.9

4.2

1.2

L

AI846048

RIKEN cDNA 2900073H19 gene

1.8

4.2

1.3

  1. * Genes with an asterisk encode proteins that localize to extracellular space
  2. Clone ID is GenBank # for BMAP clones. Clone IDs that begin with SSHI are from Rashmi Korke's mouse cDNA library
  3. L stands for low scan
  4. FC stands for fold change