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Table 2 Comparative genome hybridization to 'virulence gene' probes.

From: The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'

Genes present in all of the strains of N. lactamica tested

Genes present in some of the strains of N. lactamica tested

   Surface proteins

   Surface proteins

opa, tspA, envA, rmpM, ompH, porB, NMB1946, mtrR, mtrD, mtrE, hsf, nlpD

tspB, mtrC, omp 85, hap

   Iron acquisition

   Iron acquisition

tbp 2, fbpA, bfrA, hemH, NMB1989–NMB1991

lbpA, lbpB, bfrB, bcp, fbpB, tbp 1, NMB2132

   Pilus associated

   Pilus associated

 pglE, pilG, pilF, pglH

 pilE, pilT, NMB0051, pglA/pgtA, pglB, pglC, pglG, pglI/wbpC

   LPS biosynthesis/regulation

   LPS biosynthesis/regulation

lgtA, lgtB, lgtC, lgtD, lgtG, rfaC, rfaE, lpxB, lpxD, fabZ, pgm, phoQ/misS

rfaD, rfaF, rfaK, lgtF, lpxA, kdtA, phoP/misR,

   Others

   Others

 prc, hecB, hemagglutinin/hemolysins NMB0493 & NMB1214, endonuclease NMB0533, VapD-related NMB1753, macrophage infectivity potentiator NMB1567, sialyltransferase NMB0922, adhesion NMB0586, TonB-dependent receptor NMB1449, toxin-activating NMB1763

kat, dsbA, sodB, norZ, vapA, fur, vacJ, hemagglutinin/hemolysin NMB1768, protease NMB2127, macrophage infectivity potentiator NMB0995, toxin-activating NMB1210, TonB-dependent receptors NMB1346 & NMB1829