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Figure 6 | BMC Genomics

Figure 6

From: Identification and characterisation of human apoptosis inducing proteins using cell-based transfection microarrays and expression analysis

Figure 6

Summary of the effects of gene over-expression on the mRNA levels for genes associated with apoptotic pathways. Central pathway has been adapted from the KEGG apoptotic pathways (light blue) and BD Biosciences apoptotic pathway (light orange). A gene is shown on the pathway if present in at least one of the time points in at least three of the 4 individual treatments. Arrows within the gene mRNA boxes indicate genes with increased or decreased expression. Genes coloured red potentially increase apoptosis, genes coloured green potentially decrease apoptosis according to the literature (see Additional file 4 Table Two and Three and Additional file 5 Figures Three to Seven for Apoptosis Differentials List and more comprehensive pathways).

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