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Table 1 Proteins that are uniquely present in most epsilon proteobacteria (Campylobacterales)

From: Molecular signatures (unique proteins and conserved indels) that are specific for the epsilon proteobacteria (Campylobacterales)

Wolinella Genome ID No.

Accession Number

Length

Possible/Predicted Function

Comments

WS0030

NP_906303.1

68 aa

Probable periplasmic protein, tat-domain

All significant hits from ε-Proteobacteria

WS0086

NP_906354

181 aa

Putative helicase, gnl|CDD|14084, COG4951

All significant hits from ε-Proteobacteria

WS0133

NP_906397

397 aa

Putative integral membrane protein

All significant hits from ε-Proteobacteria

WS0134

NP_906398.1

214 aa

Conserved hypothetical protein

All significant hits from ε-Proteobacteria

WS0154

NP_906417.1

336 aa

Probable membrane protein

All significant hits from ε-Proteobacteria

WS0159

NP_906422

203 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS0169

NP_906432

92 aa

Possible membrane protein (corresponds to Cj0692c and HP0748)

All significant hits from ε-Proteobacteria

WS0172

NP_906435

675 aa

Putative membrane protein, similar to HP0358

All significant hits from ε-Proteobacteria

WS0180

NP_906442

74 aa

Related to Cbb3-type cytochrome oxidase, subunit 3, gnl|CDD|13876, COG4736

All significant hits from ε-Proteobacteria

WS0184

NP_906445.1

205 aa

Probable membrane protein

All significant hits from ε-Proteobacteria

WS0185

NP_906446

163 aa

Related to FixH protein, gnl|CDD|23975

All significant hits from ε-Proteobacteria

WS0216

NP_906474

330 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteo; E value for C. upsaliensis is higher than the threshold.

WS0260

NP_906515.1

142 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria; E value for C. lari is above the threshold.

WS0266

NP_906520

271 aa

Conserved protein, H. pylori homolog may be related to the plasminogen binding protein pgbA.

All significant hits from ε-Proteobacteria; Jonsson et al. (2004)

WS0316

NP_906567

163 aa

Conserved protein related to the RDD family; gnl|CDD|25144, pfam06271

Besides ε-Proteo, three other hits were below the threshold value; Large jump in E value from last ε-Proteo (6E-15) to the first of these hits (.003).

WS0447

NP_906689

328 aa

Putative membrane protein, corresponds to antigen P44Hh9 of H. hepaticus.

All significant hits from ε-Proteobacteria

WS0448

NP_906690

276 aa

Probable periplasmic protein

All significant hits from ε-Proteobacteria

WS0476

NP_906716

77 aa

NuoE, Putative NADH Oxidoreductase I

All significant hits from ε-Proteobacteria

WS0480

NP_906720

428 aa

Putative NADH Oxidoreductase I

All significant hits from ε-Proteobacteria

WS0490

NP_906728

778 aa

Flagellar functional protein, Pf1a

All significant hits from ε-Proteobacteria

WS0520

NP_906757.1

247 aa

TonB domain protein

All significant hits from ε-Proteobacteria

WS0563

NP_906797

164 aa

Putative integral membrane protein; identified by similarity to PIR:B71953

All significant hits from ε-Proteobacteria

WS0575

NP_906809

217 aa

Putative lipoprotein, The C. lari homolog is a secreted protein involved in flagellar motility.

All significant hits from ε-Proteobacteria.

WS0604

NP_906835

390 aa

Probable periplasmic protein

All significant hits from ε-Proteobacteria

WS0802

NP_907015

333 aa

Probable lipoprotein; identified as plasminogen binding protein pgpB.

All significant hits from ε-Proteobacteria; Jonsson et al. (2004)

WS0865

NP_907074.1

126 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria; missing in C. jejuni.

WS1039

NP_907239

156 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1040

NP_907240.1

236 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1235

NP_907415

412 aa

Putative periplasmic protein; COG5659

All significant hits from ε-Proteobacteria; not found in H. hepaticus.

WS1244

NP_907424

167 aa

Putative lipoprotein

All significant hits from ε-Proteobacteria

WS1329

NP_907504

246 aa

Putative periplasmic protein

All significant hits from ε-Proteobacteria; absent in H. pylori.

WS1344

NP_907515.1

123 aa

Putative periplasmic protein

All significant hits from ε-Proteobacteria

WS1349

NP_907520.1

110 aa

Probable membrane protein

All significant hits from ε-Proteobacteria

WS1485

NP_907639.1

89 aa

Probable integral membrane protein

All significant hits from ε-Proteobacteria

WS1495

NP_907647

87 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteo; The E value for C. lari (next best hit) above the threshold.

WS1496

NP_907648

208 aa

Probable periplasmic protein

All significant hits from ε-Proteobacteria

WS1640

NP_907771

117 aa

Probable integral membrane protein

All significant hits from ε-Proteobacteria; absent in H. pylori.

WS1730

NP_907855

183 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1755

NP_907877

168 aa

Probable lipoprotein

All significant hits from ε-Proteobacteria

WS1771

NP_907893

183 aa

Putative membrane protein

All significant hits from ε-Proteobacteria; absent in H. pylori.

WS1773

NP_907895

351 aa

Putative membrane protein

All significant hits from ε-Proteobacteria

WS1777

NP_907899.1

80 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1814

NP_907930.1

85 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1874

NP_907984

352 aa

HolA, DNA polymerase III, delta subunit; gnl|CDD|11180, COG1466

All significant hits except one from ε-Proteo; E value for Geo. metallireducens hit (.003).

WS1965

NP_908068

121 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS1990

NP_908093

118 aa

Conserved domain DUF 177: COG1399

All significant hits from ε-Proteobacteria

WS2120

NP_908218.1

162 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS2123

NP_908221

246 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteobacteria

WS2146

NP_908240

147 aa

Contains Sua5_yciO_yrdC domain involved in binding to dsRNA; gnl|CDD|15330

All significant hits except one from ε-Proteo; E value changes from 3e-19 to 2e-4 for M. synoviae

WS0230

NP_906487

432 aa

Show significant similarity to deacylase domain; gnl|CDD|12932, COG3608

Besides ε-Proteo, homologs with very low E values also present in two Desulfovibrio species.

WS2059

NP_908159

259 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteo; not found in T. denitrificans.

WS1752

NP_907874

145 aa

Conserved hypothetical protein, unknown function

All significant hits from ε-Proteo; not found in C. fetus and T. denitrificans.

WS1211

NP_907393

621 aa

Homologous to CiaB invasion antigen of C. jejuni

All significant hits from ε-Proteo; not found in H. pylori and T. denitrificans. Konkel et al. (1999)

  1. The species distribution of these proteins was determined by BLASTp and PSI-BLAST searches as described in the Methods section. Unless otherwise indicated all of these proteins are uniquely found in the following sequenced genomes: H. pylori 26695, H. pylori J99, H. hepaticus ATCC 51449, C. jejuni (various strains: NCTC 11168, RM1221, HB93-13, 84-25, CF93-6, 260.94, 11168 and 81- 176), C. lari, C. coli, C. upsaliensis, C. fetus, W. succinogenes DSM 1740 and Thiomicrospira denitrificans ATCC 33889.