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Table 1 Fold occurrence of AhR binding sites in the promoters of Aroclor 1254-regulated genes. The occurrence value of AhR binding sites in the promoters of control genes is set to 1.

From: Transcriptome profiling of human hepatocytes treated with Aroclor 1254 reveals transcription factor regulatory networks and clusters of regulated genes

Transcription factors and co-regulators of transcription (52)

Control genes

Aroclor 1254-induced

Aroclor 1254-repressed

 

Matrix similarity cut-off 0.96

1

2.62

2.78

 

Matrix similarity cut-off 0.98

1

4.28

6.87

Genes involved in regulation of cell cycle (29)

Control genes

Aroclor 1254-induced

Aroclor 1254-repressed

 

Matrix similarity cut-off 0.96

1

2.38

2.44

 

Matrix similarity cut-off 0.98

1

6.43

3.99

Genes involved in apoptosis (18)

Control genes

Aroclor 1254-induced

Aroclor 1254-repressed

 

Matrix similarity cut-off 0.96

1

0.42

2.67

 

Matrix similarity cut-off 0.98

1

1.87

5.99