Skip to main content

Table 4 Promoter analysis of 37 pairs of Aroclor 1254-regulated genes which are directly neighbored.

From: Transcriptome profiling of human hepatocytes treated with Aroclor 1254 reveals transcription factor regulatory networks and clusters of regulated genes

FIRST GENE (REFSEQ ACCESSION NUMBER)

FIRST GENE (AHR BINDING SITES)

FIRST GENE (BINDING SITES OF OTHER TFS)

SECOND GENE (REFSEQ ACCESSION NUMBER)

SECOND GENE (AHR BINDING SITES)

SECOND GENE (BINDING SITES OF OTHER TFS)

NM_003928

-

-

NM_015582

n.d.*

n.d.*

NM_005334

-

NFKB

NM_003492

1

ATF3, SP2

NM_001643

-

PPARG2

NM_032174

1

-

NM_021642

1

-

NM_002155

-

NFKB

NM_005807

-

-

NM_003292

-

SP2

NM_006623

-

-

NM_005518

-

PPARG2

NM_002061

1

SP2

NM_000350

-

-

NM_144631

2

RFXANK

NM_002707

1

PPARG2

NM_005911

-

SP2, PPARG2

NM_000821

1

PPARG2

NM_016467

-

PPARG2

NM_000534

-

NFKB

NM_022173

1

-

NM_016297

1

RFXANK, SP2

NM_006590

1

-

NM_000542

-

NRF1, PPARG2

NM_005141

-

-

NM_000508

-

-

NM_000508

-

-

NM_000509

-

-

NM_007104

-

-

NM_003214

1

SP2

NM_138446

1

-

NM_006547

-

BHLHB2

NM_003235

-

-

NM_006748

-

-

NM_001261

-

NFKB

NM_004957

-

PBX1, SP2

NM_005564

-

NFKB

NM_024112

-

SP2

NM_005489

-

SP2

NM_001261

-

-

NM_004376

-

NFKB

NM_015960

-

PPARG2

NM_005271

5

BHLHB2

NM_019054

3

-

NM_001572

-

SP2, NFKB

NM_021924

1

SP2

NM_052854

-

SP2

NM_003646

-

SP2, PPARG2

NM_006169

-

RFXANK

NM_019021

1

PPARG2

NM_021640

-

-

NM_015665

-

NFKB

NM_003348

1

-

NM_014050

-

-

NM_002937

-

PPARG2

NM_001145

-

-

NM_006599

-

NFKB, BHLHB2

NM_000903

1

NRF1

NM_003562

1

RFXANK

NM_015528

1

NFKB, RFXANK

NM_002544

1

-

NM_006495

-

-

NM_018952

-

NFKB, RFXANK

NM_004502

2

RFXANK, BHLHB2

NM_007292

2

NFKB, BHLHB2

NM_001258

-

PPARG2

NM_005359

-

-

NM_016626

1

SP2

NM_032377

-

RFXANK

NM_001611

2

BHLHB2, PPARG2

NM_018270

2

-

NM_007346

-

RFXANK, BHLHB2

NM_002626

2

SP2

NM_004928

1

SP2

  1. * Promoter sequence was not available
  2. ATF3: activating transcription factor 3, function unknown; BHLHB2: basic helix-loop-helix domain containing, class B2, anti-apoptosis, oncogenesis, hypoxia-induced; NFKB1: Nuclear Factor kappa B1, cytokine or stress-activated; NRF1: nuclear respiratory factor 1, cell growth, development; PPARG2: Peroxisome proliferator-activated receptor gamma, adipocyte differentiation, obesity, diabetes and cancer; RFXANK: regulatory factor X-associated ankyrin-containing protein, controls the cell type specificity and inducibility of MHC class II gene expression; SP2: Sp2 transcription factor, binds to GC box promoters elements.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us