Table 1 Mean values and statistical analysis for degree of conservation and paralogy. Kolmogorov-Smirnov (KS) test of the conservation score between cancer proteins and the rest of human proteins. The KS test analyses show how different two distributions are, and computes a probability (P-value) that the two distributions are equal as well as the maximum distance (D) between them.
From: Structural and functional properties of genes involved in human cancer
Genome | Average cs | KS test: conservation score (cs) | ||
|---|---|---|---|---|
Cancer genes | Non-cancer genes | D (%) | P-value | |
M. musculus | 0.79 | 0.73 | 19.5 | 1.57e-09 |
R. norvegicus | 0.77 | 0.71 | 16.7 | 4.69e-07 |
G. gallus | 0.62 | 0.56 | 14.1 | 5.36e-05 |
F. rubripes | 0.52 | 0.48 | 10.6 | 5.4e-03 |
paralogues | 0.36 | 0.40 | 9.8 | 9.1e-03 |