From: The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA
Agent | Ratio of direct single- to double-strand breaks | Ratio of single- to double-strand deoxyribose oxidation events |
---|---|---|
γ-Radiation | 35–100:1a | 35–100:1a |
Esperamicin A1 | 24:1b | 3.4:1b |
Neocarzinostatin | 6:1c | 2.2:1c |
Calicheamicin-γ1I | 1:1d | 1:24d |