The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA

BMC Genomics

Table 2 Gene expression changes in response to enediyne or γ-radiation treatment^a

	# of unique ORFS with ≥ 1.5-fold change^b
	Increased Expression	Decreased Expression	Total
Calicheamicin γ ₁ ^I	4	3	7
Esperamicin A1	5	13	18
Neocarzinostatin	26	37	63
γ-Radiation	77	74	151

^a WT S. cerevisiae was exposed to enediynes or γ-radiation and their relative transcriptomes compared. Total numbers of unique ORFs are represented that showed significant modulation (see Methods).
^b Adjusted p-value ≤ 0.1

ISSN: 1471-2164