Linkage disequilibrium interval mapping of quantitative trait loci

BMC Genomics

Table 4 Effect of sample size.

N	N _s	MSE		Difference in MSE P value	Power
		T2	HAPim		T2	HAPim
400	50	1.34	0.99	< 0.001**	0.36	0.59
	100	1.07	0.84	0.011*	0.66	0.88
	200	0.74	0.56	0.013*	0.88	0.99
800	100	1.08	0.87	0.033*	0.44	0.69
	200	0.66	0.49	0.008**	0.83	0.95
	400	0.42	0.31	0.006**	0.99	1.00

* : P < 0.05, ** : P < 0.01
Mean square errors (MSEs) in cM² of quantitative trait locus (QTL) location estimates and powers to detect the QTL obtained by the T2 and HAPim methods for various population and sample sizes. The single nucleotide polymorphism (SNP) marker spacing was 0.125 cM, t = 100, and the initial association was complete. The power was computed for a type I error of 0.05.

ISSN: 1471-2164