Table 4 The most regulated groups genes. Enriched biological processes (level 3), molecular function and chromosome distribution as defined by Gene Ontology and pathways as defined by Kegg of the differentially expressed genes.
Categorial system | Differential Expression | Term | Genes | p-value |
|---|---|---|---|---|
Biological processes | Down-regulated | REGULATION OF SIGNAL TRANSDUCTION | 4 | 0.015 |
| Â | Â | ORGANOGENESIS | 10 | 0.070 |
| Â | Â | CELL DEATH | 6 | 0.077 |
| Â | Up-regulated | ALCOHOL METABOLISM | 16 | 0.00000000000087 |
| Â | Â | MACROMOLECULE METABOLISM | 38 | 0.0000080 |
| Â | Â | BIOSYNTHESIS | 19 | 0.000086 |
| Â | Â | CATABOLISM | 16 | 0.00064 |
| Â | Â | COENZYME AND PROSTHETIC GROUP METABOLISM | 6 | 0.0028 |
| Â | Â | VITAMIN METABOLISM | 3 | 0.035 |
| Â | Â | AMINE METABOLISM | 5 | 0.063 |
Molecular function | Down-regulated | TRANSFERASE ACTIVITY, TRANSFERRING GLYCOSYL GROUPS | 6 | 0.013 |
| Â | Â | OXIDOREDUCTASE ACTIVITY, ACTING ON PEROXIDE AS ACCEPTOR | 3 | 0.030 |
| Â | Â | PROTEASE INHIBITOR ACTIVITY | 4 | 0.087 |
| Â | Up-regulated | CARBOHYDRATE KINASE ACTIVITY | 3 | 0.0096 |
| Â | Â | TRANSFERASE ACTIVITY, TRANSFERRING PHOSPHORUS-CONTAINING GROUPS | 12 | 0.013 |
| Â | Â | CARBON-OXYGEN LYASE ACTIVITY | 3 | 0.054 |
| Â | Â | PURINE NUCLEOTIDE BINDING | 15 | 0.061 |
Chromosome | Down-regulated | 2 | 17 | 0.053 |
| Â | Up-regulated | 8 | 12 | 0.021 |
Kegg pathways | Up-regulated | PENTOSE PHOSPHATE PATHWAY | 6 | 0.0000029 |
| Â | Â | GLYCOLYSIS / GLUCONEOGENESIS | 10 | 0.00011 |
| Â | Â | GALACTOSE METABOLISM | 5 | 0.00018 |
| Â | Â | FRUCTOSE AND MANNOSE METABOLISM | 5 | 0.00061 |
| Â | Â | CARBON FIXATION | 4 | 0.0018 |
| Â | Â | STARCH AND SUCROSE METABOLISM | 4 | 0.026 |