Table 2 Correlation analysis of human and mouse orthologous genes. r indicates the Pearson correlation coefficient of the A-C test p values for orthologs expressed in at least 3 normal tissues in common in human and mouse and expressed in at least one human tissue and one mouse tissue with p < threshold.
p value threshold | No. of ortholog pairs | ave r | ave r (r ≥ 0) | ave r (r < 0) | No. of pairs with r ≥ 0 | No. of pairs with r < 0 |
|---|---|---|---|---|---|---|
No | 6585 | 0.20 | 0.39 | -0.25 | 4571 (69.42%) | 2014 (30.58%) |
5.00E-02 | 5199 | 0.23 | 0.43 | -0.26 | 3591 (69.07%) | 1608 (30.93%) |
5.00E-03 | 2736 | 0.38 | 0.50 | -0.20 | 2262 (82.68%) | 474 (17.32%) |
5.00E-04 | 1889 | 0.47 | 0.56 | -0.21 | 1687 (89.31%) | 202 (10.69%) |
5.00E-05 | 1114 | 0.55 | 0.61 | -0.22 | 1012 (90.84%) | 102 (9.16%) |
1.00E-06 | 892 | 0.60 | 0.65 | -0.19 | 836 (93.72%) | 56 (6.28%) |