Figure 7

The postulated phylogenetic tree of the GIY-YIG superfamily. Only the major branches corresponding to subfamilies delineated in this work are shown. Colored blocks describe typicall domain architecture of corresponding family (the same as in Figure 1, however domain names are not shown). Blue, red, and green lines indicate bacterial, archaeal, and eukaryotic lineages. Dotted lines labeled 'HGT' indicate horizontal gene transfer events between different lineages. Dotted ellipses indicate the approximate time of intragenic duplications or other cases of horizontal gene transfer.