Figure 7

T. cruzi minicircle gRNA alignments reveal sequence bias. Sequences containing predicted gRNAs were aligned by the boundaries of the hybridization prediction. A) Spectrogram ('T'-red; 'A'-purple; 'C'-blue; 'G'-green) of aligned minicircle sequences. B) Ratios of nucleotide composition ('T'-red; 'A'-purple; 'C'-blue; 'G'-green) of aligned sequences by position.