Figure 4From: Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized miceQuantitative real-time PCR verification of selected TAM-induced genes. Overall, the microarray results for 14 TAM- and EE-induced genes were verified using QRT-PCR. The verified genes represent various affected pathways and different temporal patterns of expression. Overall, there was good correlation (average ρ = 0.8) between microarray (lines) and QRT-PCR (bars) data. Examples for six of the genes are illustrated. Statistically significant QRT-PCR differences (p < 0.05, n = 4) due to treatment are denoted by an asterisk (*).Back to article page