Table 1 Classification of single nucleotide polymorphisms (SNPs) derived from the comparison of four mouse inbred strains.
From: Mouse SNP Miner: an annotated database of mouse functional single nucleotide polymorphisms
Strains | SNP Consequence | Total SNPs (%) | Genes Effected(%) |
|---|---|---|---|
C57BL/6J vs. DBA/2J | non-synonymous | 9,079 (96.6%) | 2,956 (90.3%) |
| Â | stop-gained | 153 (1.7%) | 153 (4.7%) |
| Â | stop-lost | 26 (0.3%) | 26 (0.8%) |
| Â | splice-site | 129 (1.4%) | 129 (4%) |
| Â | frameshift | 13 (0.2%) | 13 (0.4%) |
| Â | Total | 9,400 | 3,277 |
C57BL/6J vs. 129S1/SvImJ | non-synonymous | 4,084 (96.5%) | 1,597(92.1%) |
| Â | stop-gained | 73 (1.8%) | 67 (3.9%) |
| Â | stop-lost | 7 (0.2%) | 7 (0.5%) |
| Â | splice-site | 68 (1.7%) | 63 (3.7%) |
| Â | frameshift | 1 (0.1%) | 1 (0.1%) |
| Â | Total | 4233 | 1,735 |
C57BL/6J vs. A/J | non-synonymous | 12,435 (96.2%) | 3,653 (90.7%) |
| Â | stop-gained | 262 (2.1%) | 191 (4.8%) |
| Â | stop-lost | 22 (0.2%) | 21 (0.6%) |
| Â | splice-site | 182 (1.5%) | 154 (3.9%) |
| Â | frameshift | 27 (0.3%) | 11 (0.3%) |
| Â | Total | 12,928 | 4,030 |