Figure 5

TF-Gene Map for Module 9. The TF-Gene map indicates which genes in the module can be bound (upstream) by the TFs that are significantly related to this module. Only those genes that have a binding motif in their upstream region for one of these significant TFs are annotated along the vertical axis. For these genes a dotted horizontal line is drawn. The significant TFs are annotated along the horizontal axis. For these TFs a dotted vertical line is drawn. This module, which contains all genes upregulated under sulfur limitation irrespective of the oxygen effect, can be subdivided into groups characterized by their response to oxygen presence. Genes at the top of the map (with green background) have a significantly lower expression when grown without the presence of oxygen. This group corresponds to Module 82. The middle part of the map (with white background) displays genes, which are not affected by the presence of oxygen. This group corresponds to Module 4. Genes in the bottom of the map (with red background) have higher expression when grown aerobically. This group corresponds to Module 6.