Table 1 Enriched KEGG pathways in the list of differentially expressed genes at 4 h after HAL-PDT

Total/Down regulated gene list

oxidative phosphorylation

101/79

1.0

9.1E-10

ribosome

125/119

1.2

2E-07

cell cycle

72/64

0.7

0.0015

citrate cycle (TCA cycle)

22/20

0.2

0.0041

proteasome

25/25

0.2

0.0043

ATP synthesis

32/27

0.3

0.0047

rna polymerase

21/20

0.2

0.0065

ubiquitin mediated proteolysis

32/26

0.3

0.0078

purine metabolism

92/72

0.9

0.011

pyrimidine metabolism

58/49

0.6

0.017

cholera – infection

28/20

0.3

0.02

glycolysis/gluconeogenesis

40/33

0.4

0.023

phenylalanine, tyrosine and tryptophan biosynthesis

10/8

0.1

0.027

propanoate metabolism

26/21

0.3

0.038

insulin signaling pathway

78/59

0.8

0.044

Up-regulated gene list

ubiquinone biosynthesis

8

0.2

0.019

alzheimer's disease

10

0.2

0.022

neuroactive ligand-receptor interaction

74

1.5

0.027

type i diabetes mellitus

14

0.3

0.039

focal adhesion

54

1.1

0.044

fc epsilon ri signaling pathway

23

0.5

0.065

gap junction

27

0.5

0.072

long-term depression

22

0.4

0.076

adherens junction

22

0.4

0.085

porphyrin and chlorophyll metabolism

12

0.2

0.096

hematopoietic cell lineage

24

0.5

0.099