Table 1 Inherited and epigenetic mtDNA variability. The number of subjects classified within a specific haplogroup is reported together with the number of subjects showing heteroplasmy levels higher than 5%. MtDNA haplogroups are classified according to Torroni et al., [27].
MtDNA Haplogroup | Centenarians | Controls | ||
|---|---|---|---|---|
Absolute frequency | Heteroplasmic subjects | Absolute frequency | Heteroplasmic subjects | |
H | 35 | 15 | 34 | 10 |
I | 2 | 2 | 0 | 0 |
J | 11 | 8 | 17 | 7 |
K | 10 | 6 | 16 | 6 |
T | 6 | 3 | 10 | 3 |
U | 13 | 7 | 11 | 4 |
V | 1 | 1 | 1 | 0 |
W | 2 | 1 | 4 | 3 |
X | 9 | 8 | 5 | 3 |
Other | 11 | 4 | 16 | 6 |
Total | 100 | 55 | 114 | 47 |