Figure 4

Correlation of ASR and pH values. Median ASR values across 2–3 sites and six brain regions for 126 subjects versus their brain pH values. Samples indicated in red and black were in general agreement between pH and ASR. The eight samples in blue were previously removed from analysis due to either low pH or some clinical complications (AFS is non-zero), but had normal ASR values and likely had not experienced significant agonal stress. The eight samples shown in green were previously included but had low ASR values, and should better be removed in order to reduce sample heterogeneity and possible case-control imbalance.