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Figure 5 | BMC Genomics

Figure 5

From: RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours

Figure 5

Alternative splice variants of RBM6. The five RBM6 alternative splice variants, showing deleted exons, differentially inserted regions from within intron 2, putative translation start sites (arrows) and putative stop codons (stop signs) [7]. Boxes represent exons and are not drawn to scale. Exon 3 (which is present in all RBM6 variants but absent in all RBM6-RBM5 chimeric transcripts) is depicted in blue, while exon 6 (which is differentially spliced in RBM6 variants and the RBM6-RBM5 chimeras, and contains the first of two RRM domains) is depicted in red. The forward and backward hatched boxes drawn as alternatively spliced sequences from intron 2, represent two different sequences, while the solid black box represents the same sequence in both RBM6C and RBM6D.

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