Table 2 Top 40 known genes altered by MS-275 in MC3T3-E1 cells

Induced

   AMP deaminase 3

   Musculoskeletal, embryonic nuclear protein 1

   Adenylosuccinate synthetase like 1

   Amphiregulin

   Lysyl oxidase

   Colony stimulating factor 1 (macrophage)

   Fatty acid binding protein 4, adipocyte

   Chemokine (C-C motif) ligand 9

   Solute carrier family 9 isoform 3 regulator 1

   Sorbitol dehydrogenase 1

   Troponin C, cardiac/slow skeletal

   Proline arginine-rich end leucine-rich repeat

   Glutaminyl-peptide cyclotransferase (glutaminyl cyclase)

   Inhibitor of DNA binding 1

   Solute carrier family 40, member 1

   Glutathione S-transferase, alpha 4

   Septin 4

   Voltage-dependent calcium channel gamma subunit-like

   Immediate early response 3

   Dimethylarginine dimethylaminohydrolase 1

   Similar to Normal mucosa of esophagus specific gene 1

   MAS-related GPR, member F

   Microtubule-associated protein tau

   Retinoic acid induced 3

   High mobility group AT-hook 1

   A disintegrin-like and metalloprotease with thrombospondin type 1 motif, 5

   Connective tissue growth factor

   A kinase (PRKA) anchor protein (gravin) 12

   Aldehyde dehydrogenase family 3, subfamily A1

   Galactokinase 2

   Dystrophia myotonica kinase, B15

   Thrombospondin 1

Suppressed

   Proline 4-hydroxylase, alpha polypeptide III

   Interleukin 1 receptor-like 1

   Proteasome (prosome, macropain) subunit, beta type 10

   Guanylate nucleotide binding protein 2

   Transcription factor AP-2 beta

   Sirtuin 1

   Adaptor-related protein complex AP-4, sigma 1