Table 4 Genes differentially regulated by all three HDIs
From: Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors
Gene Description | TSA | MS-275 | VPA |
|---|---|---|---|
Induced | Fold Change | ||
   Thioredoxin interacting protein | 6.865 | 1.530 | 1.404 |
   Solute carrier family 9, isoform 3 regulator 1 | 5.565 | 2.477 | 2.203 |
   Glutaminyl-peptide cyclotransferase (glutaminyl cyclase) | 5.046 | 2.387 | 2.334 |
   Sorbitol dehydrogenase 1 | 4.455 | 2.431 | 2.328 |
   Histocompatibility 2, Q region locus 5 | 4.009 | 1.634 | 1.820 |
   Phosphomannomutase 1 | 3.895 | 1.902 | 1.808 |
   RAB3D, member RAS oncogene family | 3.717 | 1.528 | 1.742 |
   Cbp/p300-interacting transactivator | 3.458 | 1.658 | 1.321 |
   Protease, serine, 11 | 3.326 | 1.836 | 1.744 |
   Syntaxin 11 | 2.488 | 1.942 | 1.750 |
   Protein phosphatase 1, regulatory (inhibitor) subunit 14c | 2.484 | 1.347 | 1.830 |
   Lysosomal-associated protein transmembrane 4B | 2.366 | 1.503 | 1.637 |
   Similar to normal mucosa of esophagus specific gene 1 | 2.099 | 2.157 | 1.930 |
   F-box and leucine-rich repeat protein 16 | 2.019 | 1.746 | 1.561 |
   HIV-1 Rev binding protein | 1.953 | 1.406 | 1.414 |
   Heat shock 70 kDa protein 5 binding protein 1 | 1.946 | 1.358 | 1.589 |
   Cysteine rich protein 2 | 1.929 | 1.847 | 1.773 |
   Asparagine synthetase | 1.597 | 1.451 | 1.248 |
   Serum deprivation response | 1.485 | 1.517 | 1.676 |
   Thymus cell antigen 1, theta | 1.419 | 1.638 | 1.676 |
   Ribonuclease, RNase A family 4 | 1.341 | 1.341 | 1.529 |
Suppressed | Â | Â | Â |
   Interleukin 1 receptor-like 1 | -1.634 | -2.035 | -1.831 |
   Low density lipoprotein receptor | -2.487 | -1.282 | -1.377 |
   Proteolipid protein 2 | -2.717 | -1.274 | -1.233 |
   PHD finger protein 15 | -4.100 | -1.498 | -1.613 |
   Vesicle-associated membrane protein 8 | -4.130 | -1.417 | -1.500 |
   Proteasome (prosome, macropain) subunit, beta type 10 | -5.362 | -2.063 | -2.035 |
   Chromosome condensation 1-like | -7.016 | -1.514 | -1.721 |
   Glutathione peroxidase 7 | -8.216 | -1.768 | -1.972 |