Table 3 Genes with up-regulated expression in the heart during iron overload

myosin, light polypeptide 7, regulatory

Myl7

NM_022879

7.68 **

myosin, light polypeptide 4, alkali

Myl4

NM_010858

6.32 **

seminal vesicle secretion 5

Svs5

NM_009301

5.21 **

seminal vesicle protein 2

Svp2

NM_009300

4.25 **

myosin binding protein H-like

Mybphl

NM_026831

4.14 **

angiopoietin-like 4

Angptl4

NM_020581

2.79 *

seminal vesicle protein, secretion 2

Svs2

NM_017390

2.61 **

pyruvate dehydrogenase kinase, isoenzyme 4

Pdk4

NM_013743

2.06 *

S100 calcium binding protein A8 (calgranulin A)

S100a8

NM_013650

1.96 *

S100 calcium binding protein A9 (calgranulin B)

S100a9

NM_009114

1.95 *

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

Hmgcs2

NM_008256

1.82 **

Ras-related associated with diabetes

Rrad

NM_019662

1.81 **

thioredoxin interacting protein

Txnip

NM_023719

1.78 *

secretory leukocyte protease inhibitor

Slpi

NM_011414

1.69 **

dickkopf homolog 3 (Xenopus laevis)

Dkk3

NM_015814

1.68 **

START domain containing 10

Stard10

NM_019990

1.68 **

D site albumin promoter binding protein

Dbp

NM_016974

1.65 *

lectin, galactose binding, soluble 4

Lgals4

NM_010706

1.65 **

cytochrome P450, family 26, subfamily b, polypeptide 1

Cyp26b1

NM_175475

1.62 **

2310043N10Rik

XM_979471

1.55 *

cold inducible RNA binding protein

Cirbp

NM_007705

1.49 *

FBJ osteosarcoma oncogene

Fos

NM_010234

1.49 **

2900060B14Rik

1.49 *

early growth response 1

Egr1

NM_007913

1.46 *

1810015C04Rik

NM_025459

1.45 *

seminal vesicle secretion 1

Svs1

NM_172888

1.44 **

Iroquois related homeobox 3 (Drosophila)

Irx3

NM_008393

1.43 **

BC031353

NM_153584

1.43 *

folliculin interacting protein 1

Fnip1

NM_173753

1.42 **

myosin, heavy polypeptide 7, cardiac muscle, beta

Myh7

NM_080728

1.42 **

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Cited2

NM_010828

1.41*

2610035D17Rik

XM_990633

1.41 **

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1

Adamts1

NM_009621

1.40 *

fructose bisphosphatase 2

Fbp2

NM_007994

1.40 *

2300009N04Rik

1.40 *