Table 3 Cytogenetic and molecular data for the 16 TEL/AML1 (ETV6/RUNX1)-positive patients
Patients | TEL/AML1 (ETV6/RUNX1) Fusion gene | RISK GROUP | KARYOTYPE | AML1(RUNX1) Copy-Number FISH | TEL(ETV6) Deletion FISH |
|---|---|---|---|---|---|
3 | TEL/AML1 | SR | 45, XY, der(3)t(3;8),-8, add(12)p?12?13 | 3 | YES |
5 | TEL/AML1 | SR | 46, XY | 2 | YES |
9 | NONE | SR | 53, XXY,+6,+10,+10,+14,+18,+?i(21q)[16]/46, XY[7] | 4 | NO |
12 | TEL/AML1 | SR | 46, XY | 2 | NO |
13 | TEL/AML1 | SR | 49, XX,+10,+15,+der(21)[1]/49, XX, idem, del(12)[6]/50XX, idem,+18[15]/50XX, idem, del(12),+18[2]/46XX[6] | 3 | YES |
17 | TEL/AML1 | SR | 47, XY, add(8p),-10, del(11q),+21,+mar[18]/46XY[4] | 2 | YES |
18 | TEL/AML1 | HR | 46, XY, add(19)(p or q) | 2 | YES |
23 | TEL/AML1 | SR | 50, XY,+8,?der(12),+21,+mar[4]/46XY)[26] | 3 | NO |
32 | TEL/AML1 | HR | 47, XY, t(3;14)(q?13;q?23),+21[18]/46, XY)[1] | 4 | NO |
33 | TEL/AML1 | SR | 46, XY | 2 | NO |
35 | TEL/AML1 | SR | 46, XY | 2 | NO |
40 | TEL/AML1 | SR | 45, X,-X, del(6)(q12qter) | 2 | YES |
41 | TEL/AML1 | SR | failure | 2 | NO |
43 | TEL/AML1 | SR | 46, X,?del(Xq)[20]/46, XX[16] | 2 | YES |
47 | TEL/AML1 | SR | 46, XY | 2 | NO |
48 | TEL/AML1 | SR | 46, XY[25] | 2 | NO |
53 | TEL/AML1 | SR | 46, XY, t(1;8)?(q31;q24)t(X;17)?(q21;p13) [20]/46, XY[3] | 2 | NO |