From: Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells
 |  | Fold changea) |  |  |  | ||||
---|---|---|---|---|---|---|---|---|---|
 | Accession No. | W vs H | W1 vs H1 | W1 vs H2 | W2 vs H1 | W2 vs H2 | Symbol | Chromosome | Gene description |
Down-regulated | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Cell structure/cell adhesion | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AA867778 | 2.1 | 2.4 | 2.6 | 1.7 | 1.8 | Actn1 | 12 | Actinin, alpha 1 |
Cell cycle/cell proliferation/cell death | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AJ223782 | 2.0 | 1.8 | 1.7 | 2.5 | 2.3 | Sept7 | 9 | Septin7 (Cdc10) |
Immune response | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | X05475 | 2.1 | 2.5 | 1.8 | 2.6 | 1.9 | C9 | 15 | Complement component C9 |
Metabolism | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | L42996 | 3.0 | 1.7 | 3.7 | 2.7 | 5.8 | Dbt | 3 | Nuclear-encoded mitochondrial acyltransferase |
 | AF026075 | 2.4 | 1.8 | 4.3 | 1.7 | 4.0 | Sult3a1 | 10 | Sulfotransferase-related protein (SULT-X2) |
Protein biosynthesis/degradation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | M27347 | 3.2 | 3.4 | 3.2 | 3.1 | 3.0 | Ela1 | 15 | P6-5 gene, 3' end (elastase 1) |
Signaling | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI563623 | 2.3 | 2.9 | 1.9 | 2.9 | 1.8 | Pkn2 | 3 | Protein kinase N2 |
Transcription/replication | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AF010405 | 4.9 | 6.8 | 3.2 | 8.5 | 4.1 | Hfh-1L | 13 | HNF-3/forkhead homolog 1 like |
 | L20450 | 3.7 | 3.1 | 2.7 | 5.0 | 4.3 | Zfp97 | 17 | Zinc finger protein 97 |
 | AW048355 | 2.1 | 1.6 | 1.9 | 2.3 | 2.8 | Phf17 | 3 | PHD finger protein 17 |
 | AI848996 | 2.1 | 2.2 | 2.3 | 2.0 | 2.1 | Dhx40 | 11 | DEAH box polypeptide 40 |
 | AW123909 | 2.1 | 1.5 | 1.9 | 2.2 | 2.9 | Rbpms | 8 | RNA binding protein gene with multiple splicing |
Transport | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | D86066 | 3.2 | 2.3 | 4.4 | 2.6 | 4.8 | Rab5ep-pending | 11 | Rabaptin-5 |
Others | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI835016 | 2.4 | 2.1 | 2.3 | 2.5 | 2.7 | Hps4 | 5 | Light ear protein (1e) |
Unknown | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI848841 | 2.1 | 2.2 | 1.6 | 2.7 | 2.0 | A230106A15Rik | 13 | Unknown |
Up-regulated | Â | H vs W | H1 vs W1 | H1 vs W2 | H2 vs W1 | H2 vs W2 | Â | Â | Â |
Cell cycle/cell proliferation/cell death | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | X95280 | 3.0 | 2.8 | 2.7 | 3.4 | 3.2 | G0s2 | 1 | GOS2-like protein |
Cell structure/cell adhesion | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI132491 | 2.1 | 1.9 | 2.6 | 1.6 | 2.2 | Bysl | 17 | Bystin-like |
Immune response | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | J00475 | 3.1 | 9.2 | 2.8 | 4.2 | 1.3 | Iga | 12 | Germline IgH chain gene, DJC region-segment D-FL16.1 |
Metabolism | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | M63245 | 3.2 | 2.8 | 4.0 | 2.6 | 3.7 | Alas1 | 9 | Amino levulinate synthase (ALAS-H) |
 | AW121625 | 2.5 | 2.8 | 2.4 | 2.6 | 2.3 | Galnt11 | 5 | Polypeptide GalNAc transferase 11 |
 | Y15003 | 2.1 | 1.8 | 1.9 | 2.3 | 2.5 | St3gal5 | 6 | Beta-galactoside alpha-2,3-sialyltransferase 5 |
Signaling | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | L76567 | 4.1 | 1.8 | 2.3 | 5.5 | 7.0 | Shp1 | 4 | Shp gene |
Transcription/replication | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI553024 | 2.4 | 2.4 | 1.5 | 3.8 | 2.4 | Zbtb16 | 9 | Zinc finger and BTB domain containing 16 |
Unknown | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | AI042964 | 7.1 | 7.1 | 8.4 | 5.9 | 7.1 | 0610005C13Rik | 7 | Hypothetical protein |
 | AI593759 | 3.7 | 3.0 | 4.0 | 3.4 | 4.6 | 9530051K01Rik | 7 | Hypothetical protein |
 | AI019679 | 2.3 | 10.0 | 1.4 | 9.4 | 1.3 | 1100001G20Rik | 11 | Hypothetical protein |