Figure 9

Phylogram of the PPM type of serine/threonine phosphatases. This phylogram includes PPM catalytic domains from human, S. cerevisiae and A. thaliana. Phosphatase domains are indicated by systematic gene IDs. Sequences are colour-coded by organism: blue for T. cruzi (Tc), T. brucei (Tb) and L. major (Lmj F); red for human (Hs); brown for S. cerevisiae (Sc) and green for A. thaliana (At). Most sequence IDs are from the Swiss-Prot database but there are also NCBI database accession numbers used (beginning 'NP'). Results of the four phylogenetic methods are shown: bootstrap values > 70 are black for Neighbour-Joining, brown for Bayesian and purple for Maximum Parsimony. Asterisks (*) show Maximum Likelihood support. Dashed lines show phylogenetic relationships as indicated in an initial tree from an ungapped alignment. Each clade was analysed separately to obtain robust phylogenetic analysis and these were then combined to show the whole PPM family.