Figure 2
From: Predicting protein function by machine learning on amino acid sequences – a critical evaluation
Discrimination between proteins of known and unknown function. The results of five random splits of test and training set are shown, and for comparison the lower two rows show the median performance of the function prediction classifier and the 'transport and binding' classifier for each species. For each species, except M. genitalium the average performance on the known-vs.-unknown task is better than on the function prediction task. In the case of T. pallidum, known and unknown proteins can be distinguished with almost perfect performance.