Table 1 Function of genes verified via real-time PCR
Gene Name | Tissue | Major Functions | Cellular location |
|---|---|---|---|
Id1 | Mixed tissue | DNA binding; development; negative regulation of transcription from Pol II promoter; regulation of angiogenesis | Nucleus |
Cox6a2 | Mixed tissue | Cytochrome C oxidase activity: electron transport; oxidoreductase activity; respiratory chain complex IV | mitochondrion |
Ap | Liver | Phosphodiesterase activity: catalysis of the reaction; regulate cyclic nucleotide signaling; signal transduction regulation; second messenger molecules. | Cell and nuclear membrane; subcellular domains |
Ldha | Mixed tissue | L-lactate dehydrogenase activity: glycolysis; lactate dehydrogenase activity: oxidoreductase activity | Cytoplasm |
Gpnmb | Bone | bone mineralization; osteoblast differentiation | Plasma membrane |
Tpi1 | Mixed tissue | Fatty acid biosynthesis; gluconeogenesis; glycolysis; isomerase activity; metabolism; pentose-phosphate shunt; triose-phosphate isomerase activity | Mitochondrion |
Pgk1 | Mixed tissue | Glycolysis; kinase activity; phosphoglycerate kinase activity; phosphorylase kinase activity; phosphorylase kinase complex; transferase activity | Mitochondrion |