Table 2 List of top 20 up and down regulated genes in the head kidney of trout, 24 and 72 hours after i.p. injection of attIHNV. Genes were selected for significant differential expression at p < 0.01 (FDR < 0.05). Values are expressed as FC, fold change.
24 hours UP | Â | Â | Â | 72 hours UP | Â | Â | Â |
|---|---|---|---|---|---|---|---|
Clone ID | Clone Name | FC | p | Clone ID | Clone Name | FC | p |
EXOB2_B10 | Hemoglobin beta chain | 19.46 | 0.000 | est03e08 | Hypothetical-fish 36 | 3.06 | 0.000 |
HST0001_C04 | Hemoglobin alpha chain | 11.19 | 0.000 | CA343473 | C3a anaphylatoxin chemotactic receptor | 2.98 | 0.000 |
KVkm2_A01 | Unknown-219 | 10.93 | 0.000 | EXOB2_G11 | Stanniocalcin-1 | 2.93 | 0.000 |
HST0001_D04 | Alpha-globin I-2 | 10.93 | 0.000 | EXOB1_B02 | Hypothetical-fish 34 | 2.84 | 0.000 |
EXOB4_A03 | Carbonic anhydrase | 10.57 | 0.000 | KVkm2_H07 | Unknown-226 | 2.77 | 0.000 |
CA366564 | Huntingtin | 8.52 | 0.000 | EXOB3_A01 | Unknown-103 | 2.73 | 0.000 |
EXOB2_B12 | RING finger protein 103 | 8.34 | 0.000 | CA363723 | Cyclin C | 2.64 | 0.000 |
HST0001_C07 | Unknown-213 | 7.60 | 0.000 | EXOB4_H01 | Unknown-132 | 2.63 | 0.000 |
ENH2_E07 | Unknown-3 | 7.04 | 0.000 | est04c02 | Unknown-53 | 2.61 | 0.000 |
EXOB4_G09 | Histone H14 | 6.94 | 0.000 | HK0002_G04 | Fructose-bisphosphate aldolase A | 2.45 | 0.000 |
EXOB4_H06 | Alpha-globin 1-3 | 6.63 | 0.000 | EST1-3A_H03 | Unknown-76 | 2.42 | 0.000 |
utu01e09 | Embryonic alpha-type globin2+collagen alpha 2(1) | 4.94 | 0.000 | CA358107 | Ectonucleoside triphosphate diphosphohydrolase 1 | 2.42 | 0.000 |
HK0002_G02 | Creatine kinase, sarcomeric mitochondrial precursor | 4.49 | 0.000 | CA378361 | Ubiquitin ligase SIAH1 | 2.40 | 0.000 |
HK0001_C08 | Galectin-9 (VHSV-induced protein)-3 | 4.14 | 0.000 | HK0001_H12 | Unknown-162 | 2.35 | 0.000 |
CA361101 | Regulator of G-protein signaling 1-2 | 4.03 | 0.000 | CA342204 | TNF receptor associated factor 3 | 2.33 | 0.000 |
est02a11 | Ig kappa chain V-IV region B17-2 | 3.19 | 0.000 | EST1-3A_H05 | Adenosine deaminase 3 | 2.31 | 0.000 |
CA343473 | C3a anaphylatoxin chemotactic receptor | 3.00 | 0.000 | est04f10 | Hypothetical-fish 1 | 2.30 | 0.000 |
est04b01 | Similar to rRNA (Vangl2) | 2.69 | 0.000 | KVkm2_H11 | Unknown-228 | 2.30 | 0.000 |
HST0001_D02 | ATP-binding cassette, sub-family F, member 2 | 2.58 | 0.000 | HKT0001_A11 | Hypothetical-fish 11 | 2.28 | 0.000 |
CA384134 | G1/S-specific cyclin D2 | 2.56 | 0.000 | CA355893 | DnaJ homolog subfami.B member 2 | 2.26 | 0.000 |
24 hours DOWN | Â | Â | Â | 72 hours DOWN | Â | Â | Â |
est01e10 | Tolloid-like protein (nephrosin)-1 | -2.60 | 0.000 | EXOB2_G02 | Profilin-1 | -2.13 | 0.000 |
est03c04 | Matrix metalloproteinase-9 | -2.70 | 0.000 | EXOB2_F12 | 60S ribosomal protein L7a-1 | -2.13 | 0.000 |
HST0001_C03 | Plasminogen precursor-2 | -2.72 | 0.000 | est02g11 | Cytochrome c oxidase subunit I-1 | -2.14 | 0.000 |
KVkm2_H10 | Unknown-227 | -2.76 | 0.000 | HK0001_H03 | 60S ribosomal protein L26 | -2.14 | 0.000 |
CA34828 | CCAAT/enhancer binding protein beta | -3.05 | 0.000 | HK0003_A12 | Heterogeneous nuclear ribonucleoprotein A1-1 | -2.16 | 0.000 |
EXOB2_D05 | Matrix metalloproteinase 9-2 | -3.07 | 0.000 | EXOB1_H12 | NADH dehydrogenase subunit 4 | -2.23 | 0.000 |
est02f08 | Serine protease-like protein-1 | -3.21 | 0.000 | HK0002_D07 | Unknown-172 | -2.24 | 0.000 |
EST1-3A_A09 | Serine protease-like protein-2 | -3.25 | 0.000 | EXOB3_G03 | 60S acidic ribosomal protein P2 | -2.31 | 0.000 |
HK0003_C11 | Tropomyosin alpha 3 chain-1 | -3.34 | 0.000 | EXOB2_G09 | Cytochrome c oxidase subunit I-2 | -2.34 | 0.000 |
utu03e06 | Parvalbumin alpha-3 | -3.50 | 0.000 | HST0001_D04 | Alpha-globin I-2 | -2.37 | 0.000 |
CA370329 | Lysozyme C precursor | -3.90 | 0.000 | ENH2_H06 | Unknown-5 | -2.46 | 0.000 |
HK0003_C08 | Parvalbumin alpha-2 | -3.99 | 0.000 | est04c05 | Ferritin heavy chain-1 | -2.54 | 0.000 |
utu04h1 | Myosin light chain 2-2 | -4.13 | 0.000 | P_46 | ATPase 6 | -2.56 | 0.000 |
utu02c02 | Myosin heavy chain, skeletal, adult 1-1 | -4.30 | 0.000 | utu02b07 | Cytochrome c oxidase subunit II | -2.64 | 0.000 |
Hete0002_A07 | Metallothionein-IL | -4.49 | 0.000 | KVkm2_H10 | Unknown-227 | -2.67 | 0.000 |
HK0003_E07 | Myosin light chain 2-1 | -4.49 | 0.000 | EST1-3A_H07 | Cytochrome b-1 | -2.86 | 0.000 |
HK0002_D07 | Unknown-172 | -5.04 | 0.000 | est02h09 | Nonhistone chromosomal protein HMG-17 | -3.07 | 0.000 |
EXOB1_A03 | Metallothionein A | -5.05 | 0.000 | CA370329 | Lysozyme C precursor | -3.08 | 0.000 |
est01c04 | Unknown-11 | -6.17 | 0.000 | EXOB1_C02 | Unknown-83 | -3.44 | 0.000 |
HK0002_F05 | Myosin heavy chain, skeletal, fetal | -7.31 | 0.000 | EXOB2_G01 | Leukocyte cell-derived chemotaxin 2 | -3.56 | 0.000 |