Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome

Table 1 Estimated relative mutation rates for pairs of reciprocal substitutions^a

Transition/Transversion	CpG	Substitution pair	RMR
Transversion	nonCpG^b	C:G > A:T	2.0
Transversion	nonCpG^b	C:G > G:C	2.0
Transition	nonCpG	C:G > T:A	7.3
Transversion	CpG	C:G > A:T	16.0
Transversion	CpG	C:G > G:C	16.0
Transition	CpG	C:G > T:A	96.7
Transversion	nonCpG	A:T > C:G	2.2
Transition	nonCpG	A:T > G:C	7.3
Transversion	nonCpG	A:T > T:A	1.8

^aOriginal data and computing of relative mutation rates can be found in Additional file 1.
^bRelative mutation rate is one per transversion C > A or G > T giving 2 for the C:G > A:T pair

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