Figure 2
From: Topoisomerase II inhibition involves characteristic chromosomal expression patterns
Overexpression of c-myc: Frequency of the number of distances < 100 kbp between transcription start sites (TSSs). The number of distances < 100 kbp between TSSs was calculated for 100 randomized gene lists on the one hand and for the significant gene list stemming from lung tissue of a mouse transgenic line overexpressing the oncogene c-myc on the other hand. The number of distances < 100 kbp between TSSs of the significantly regulated genes is marked by a black arrow in the histograms.