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Figure 1 | BMC Genomics

Figure 1

From: An in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transporters

Figure 1

Sequence logo[64]visualization of the 5 different T-box motifs. Both the consensus sequence and relative conservation of individual residues is displayed. Motif 1 (information content: 19.2 bits) displays the motif used to perform the T-box identification. Validation was performed by checking the presence of motif 2 (29.7 bits) or 3 (20.9 bits) together with motifs 4 (31.4 bits) and 5 (25.8 bits). Motif 1 includes the (a-specific) tRNA interaction site (T-box sequence, consensus GGTGG) located in the antiterminator loop. The other motifs include different parts of the specifier loop [23, 26]: GNTG- and AG-box in motif 2 and 4, TGA-, AGGA- and AGTA-box in motif 3 and a conserved part of the specifier loop in motif 5 (GAG). The specifier codon is to be found within 1 – 5 nucleotides upstream of this conserved GAG.

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BMC Genomics

ISSN: 1471-2164

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