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Table 3 Selected UCR Motifs

From: Comparative genomics of small RNA regulatory pathway components in vector mosquitoes

    

Proportion of UCRs with Motif

Median Motifs per UCR

Motif

FET p value

BH

Enriched over genome?

miRNA

siRNA

PIWI

miRNA

siRNA

PIWI

NFkB2

not sig.^

not sig.

No

0.188

0.250

0.100

1.0

1.0

1.0

NFkB4

not sig.

not sig.

No

0.313

0.438

0.460

1.0

1.0

1.0

NFkB7*

not sig.

not sig.

No

0.188

0.375

0.280

1.0

1.0

1.0

BRC_Z1

not sig.

not sig.

No

0.813

0.313

0.540

1.0

1.0

1.0

BRC_Z2

not sig.

not sig.

No

0.563

0.688

0.620

1.0

1.0

1.0

Pathway-specific

      

miRNA

siRNA

PIWI

M19 (miRNA)

not sig.

not sig.

Yes

0.188

0.100

0.033

4.5

1

1

M21 (miRNA)

not sig.

not sig.

Yes

0.219

0.100

0.067

2

2

1

M24 (siRNA)

not sig.

not sig.

Yes

0.063

0.400

0.200

1

14

1

M26 (siRNA)

not sig.

not sig.

Yes

0.031

0.250

0.033

2

3

2

M30 (PIWI)

not sig.

not sig.

Yes

0.000

0.000

0.060

NA

NA

5

Species-Specific

   

Aae

Aga

Cpi

Aae

Aga

Cpi

M1 (Aedes)

not sig.

not sig.

Yes

0.188

0.100

0.033

1.5

1.5

1

M2 (Aedes)

not sig.

not sig.

Yes

0.219

0.100

0.067

2

2

1

M3 (Aedes)

not sig.

not sig.

Yes

0.094

0.000

0.033

9

NA

1

M7 (Anopheles)#

not sig.

not sig.

Yes

0.063

0.400

0.200

10.5

1.5

1

M8 (Anopheles) #

not sig.

not sig.

Yes

0.031

0.250

0.033

10

1

1

M9 (Anopheles)

< 0.001

0.002

No

0.000

0.400

0.300

NA

6

1

M12 (Culex)+

not sig.

not sig.

Yes

0.031

0.000

0.067

1

NA

21

M13 (Culex)+

not sig.

not sig.

Yes

0.031

0.000

0.067

1

NA

21

M17 (Culex)

< 0.001

0.002

No

0.094

0.100

0.533

1

1

1

  1. "^", see Additional File 4 for details. "*", for NFkB7 only, significance scores were based on the presence of 2 or more hits per UCR. "#", enriched in an siRNA pathway specific manner. "+", enriched in an miRNA pathway specific manner. "BH", Benjamini-Hochberg test, cut-off = 0.05. "FET", Fisher's Exact test, cutoff = 0.01. "NA", not applicable. "Aae", Ae. aegypti, "Aga", An. gambiae, "Cpi", Cx. pipiens.