Figure 1

Circular representations of the genome of B. petrii. The circles represent, from the outside in; 1+2, all transcribed CDS (clockwise and counter-clockwise, respectively) [Colour coding: dark blue, pathogenicity/adaptation; black, energy metabolism; red, information transfer; dark green, surface associated; cyan, degradation of large molecules; magenta, degradation of small molecules; yellow, central/intermediary metabolism; pale green, unknown; pale blue, regulators; orange, conserved hypothetical; brown, pseudogenes; pink, phage and IS elements; grey, miscellaneous]; 3, genomic islands [grey: GI; red (clockwise): GI1, 2, 3 and 6; dark purple: GI4; blue: GI5; Green: GI7; light purple: prophages; brown: remnants of prophages or GI]; 4, aromatic compounds metabolism (purple) and bug (green) genes, a gene family which has experienced a vast amplification in the Bordetellae possibly encoding periplasmic binding proteins [53]; 5, IS elements; 6, GC content (plotted using a 10 kb window); 8, GC deviation [(G-C)/(G+C) plotted using a 10 kb window; khaki indicates values > 1, purple < 1].