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Figure 5 | BMC Genomics

Figure 5

From: The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains

Figure 5

SH2-recognized Tyr-SLiMs in membrane proteins are conserved in the cytoplasmic but not the extra-cellular region. (A) The conservation signal in SH2-recognized Tyr-SLiMs is stronger in the cytoplasmic region than in the extra-cellular region in both Type I and II membrane proteins, especially in Type I membrane proteins from specific functional classes (including cytokine/immune receptors, receptor kinases/phosphatases, cell surface receptors, and adhesion molecules). (B) Examples of conservation profiles that compare extra-cellular regions to cytoplasmic regions.

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BMC Genomics

ISSN: 1471-2164

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