Figure 3
From: p53 induces distinct epigenetic states at its direct target promoters
Overlap between wt p53 DNA binding and changes in histone acetylation. The Venn diagram shows the overlap between promoters bound by wt p53 and promoters with significant changes in acetylation of histones H3 and H4 in response to wt p53 overexpression. The number of promoters with increased acetylation are marked with a (+) sign and those with decreased acetylation with a (-) sign.