Table 1 Top 10 canonical pathways influenced by fasting
pathway | pathway group | p- value | genes |
|---|---|---|---|
glycolysis and gluconeogenesis | metabolic maps/carbohydrate metabolism | 2.32e-07 | 9/36 |
urea cycle | metabolic maps/amino-acid metabolism | 2.61e-07 | 8/27 |
PPARα regulation of lipid metabolism | regulation of metabolism/regulation of lipid metabolism | 3.57e-07 | 8/28 |
peroxisomal straight-chain fatty-acid β-oxidation | metabolic maps/lipid metabolism | 2.51e-06 | 5/10 |
mitochondrial long-chain fatty- acid β-oxidation | metabolic maps/lipid metabolism | 2.74e-06 | 6/17 |
metabolism of sulphur-containing amino acids | metabolic maps/amino-acid metabolism | 4.02e-06 | 6/18 |
peroxisomal branched-chain fatty- acid oxidation | metabolic maps/lipid metabolism | 8.04e-06 | 6/20 |
taurine metabolism | metabolic maps/amino-acid metabolism | 1.96e-05 | 6/23 |
mitochondrial unsaturated fatty- acid β-oxidation | metabolic maps/lipid metabolism | 2.69e-05 | 5/15 |
TCA | metabolic maps/amino-acid metabolism | 1.25e-04 | 4/20 |