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Table 1 The temporal pattern of genes up-regulated with IGF-1 treatment

From: Insulin-like growth factor-1 coordinately induces the expression of fatty acid and cholesterol biosynthetic genes in murine C2C12 myoblasts

Affy. Id.

Symbol

Genes up-regulated at 1 hr only

Fold Change

1452519_a_at

Zfp36

Zinc finger protein 36

2.2

1450295_s_at

Pvr

Poliovirus receptor (pvr)

2.2

1427186_a_at

Mef2a

Myocyte enhancer factor 2A

2.2

1418102_at

Hes1

Hairy and enhancer of split 1

2.2

1416442_at

Ier2

Immediate early response 2

2.2

  

Genes up-regulated at 1 & 2 hrs

 

1427683_at

Egr2

Early growth response 2

2.6

1427174_at

Phlda3

Pleckstrin homology-like dom. family A, member 1

2.4

1419816_s_at

Zfp36l2

Zinc finger protein 36, C3H type-like 2

2.4

1418835_at

Phlda1

Pleckstrin homology-like dom. family A, member 1

2.4

1437626_at

Zfp36l2

Zinc finger protein 36, C3H type-like 2

2.2

1436026_at

Zfp703

zinc finger protein 703

2.2

  

Genes up-regulated at 1 & 4 hrs

 

1421077_at

Sertad3

SERTA domain containing 3

2.5

  

Genes up-regulated at 1, 2 & 4 hrs

 

1455899_x_at

Socs3

Suppressor of cytokine signalling 3

5.0

1451382_at

Chac

Cation transport regulator-like 1

5.0

1428306_at

Ddit4

DNA-damage-inducible transcript 4

4.0

1417871_at

Hsd17b7

Hydroxysteroid (17-beta) dehydrogenase 7

3.6

1424022_at

Osgin1

Oxidative stress induced growth inhibitor 1

3.3

1418025_at

Bhlhb2

Basic helix-loop-helix domain containing, class B2

3.3

1416029_at

Klf10

Kruppel-like factor 10

3.2

1424709_at

Sc5d

Sterol-C5-desaturase

3.1

1456212_x_at

Socs3

Suppressor of cytokine signaling 3

2.9

1448742_at

Snai1

Snail homolog 1

2.9

1448170_at

Siah2

Seven in absentia 2

2.7

1434204_x_at

Shmt2

Serine hydroxymethyl transferase 2 (mito)

2.2

  

Genes up-regulated at 2 hrs only

 

1421228_at

Ccl7

Chemokine (C-C motif) ligand 7

4.5

1422213_s_at

Foxh1

Forkhead box H1

4.5

1449227_at

Ch25h

Cholesterol 25-hydroxylase

4.0

1438097_at

Rab20

RAB20, member RAS oncogene family

3.3

1426706_s_at

Xylb

Xylulokinase homolog (H. influenzae)

3.3

1421215_a_at

Slmap

Sarcolemma associated protein

3.1

1428888_at

Tmem33

Transmembrane protein 33 clone

3.1

1448125_at

Rit2

Ras-like without CAAX 2

3.0

1452402_at

Uchl3

Ubiquitin carboxyl-terminal esterase L3

3.0

1452412_at

Hoxc8

Homeo box C8

2.9

1426958_at

Rps9

Ribosomal protein S9

2.9

1425624_at

Epm2aip1

EPM2A (laforin) interacting protein 1

2.8

1427583_at

Rik

RIKEN cDNA 4921505C17 gene

2.8

1441023_at

Eif2s2

Eukaryotic translation initiation factor 2 beta

2.7

1426065_a_at

Trib3

Tribbles homolog 3 (Drosophila)

2.6

425362_at

Hrb1

HIV-1 Rev binding protein-like

2.6

1424950_at

Sox9

SRY-box containing gene 9

2.6

1455904_at

Gas5

Growth arrest specific 5

2.5

1456094_at

Usp36

Ubiquitin specific peptidase 36

2.5

1449414_at

Zfp53

Zinc finger protein 53

2.5

1453806_at

Ndufb2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2

2.5

1417597_at

Cd28

CD28 antigen

2.5

1422851_at

Hmga2

High mobility group AT-hook 2

2.4

1450780_s_at

Hmga2

High mobility group AT-hook 2

2.4

1445116_at

Usp25

Ubiquitin-specific processing protease

2.4

1425500_x_at

Coro2a

Coronin, actin binding protein 2A

2.4

1449578_at

Supt16h

Suppressor of Ty 16 homolog

2.4

1449110_at

Rhob

Ras homolog gene family, member B

2.3

1425281_a_at

Tsc22d3

TSC22 domain family 3

2.3

1437658_a_at

Snord22

small nucleolar RNA, C/D box 22

2.3

1420961_a_at

Ivns1abp

Influenza virus NS1A binding protein

2.3

1421512_at

Cep250

Centrosomal protein 250

2.3

1453497_a_at

Piga

Phosphatidylinositol glycan, class A

2.3

1416693_at

Foxc2

Forkhead box C2

2.2

1450781_at

Hmga2

High mobility group AT-hook 2

2.2

1438527_at

Rpl3

Ribosomal protein L3

2.2

1448171_at

Siah2

Seven in absentia 2

2.2

1424607_a_at

BC003993

K0208G08-3 NIA Mouse clone

2.2

1420380_at

Ccl2

Chemokine (C-C motif) ligand 2

2.2

1417395_at

Klf4

Kruppel-like factor 4

2.2

1431030_a_at

Rnf14

Ring finger protein 14

2.2

1448183_a_at

Hif1a

Hypoxia inducible factor 1, alpha subunit

2.1

1419157_at

Sox4

SRY-box containing gene 4

2.1

1418158_at

Trp63

Transformation related protein 63

2.1

1421000_at

Cnot4

CCR4-NOT transcription complex, subunit 4

2.1

1452161_at

Tiparp

TCDD-inducible poly(ADP-ribose) polymerase

2.0

1425279_at

Pdik1l

PDLIM1 interacting kinase 1 like

2.0

1453840_at

Pabpc1

Poly A binding protein, cytoplasmic 1

2.0

1416123_at

Ccnd2

Cyclin D2

2.0

1417924_at

Pak3

P21-activated kinase 3

2.0

  1. The temporal pattern of genes up-regulated in mouse myoblasts following IGF-1 treatment is tabulated based on their Venn distribution. Shown are genes up-regulated at: 1 hr only; 1 & 2 hrs; at 1 & 4 hrs; 1, 2 & 4 hrs and 2 hrs only (Please see Additional file 1 for genes up-regulated at 2 & 4 hrs and 4 hrs only).