Open Access

Erratum to: Uncovering rate variation of lateral gene transfer during bacterial genome evolution

BMC Genomics20089:556

DOI: 10.1186/1471-2164-9-556

Received: 20 October 2008

Accepted: 25 November 2008

Published: 25 November 2008

The original article was published in BMC Genomics 2008 9:235
On page 11 of our publication [1], the correction for missing data in a discrete Γ distribution was conducted as
Q + = i = 1 N L + i = i = 1 N j = 1 M p j L i ( μ j ) 1 L i ( μ j ) . MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xI8qiVKYPFjYdHaVhbbf9v8qqaqFr0xc9vqFj0dXdbba91qpepeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=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@5E52@
This correction, equation (1), is only correct when the category probabilities p j have no effect on observability. Because the category probabilities have an effect on observability, the appropriate correction is
Q + = i = 1 N L + i = i = 1 N j = 1 M p j L i ( μ j ) 1 j = 1 M p j L i ( μ j ) . MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xI8qiVKYPFjYdHaVhbbf9v8qqaqFr0xc9vqFj0dXdbba91qpepeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemyuae1aaSbaaSqaaiabgUcaRaqabaGccqGH9aqpdaqeWbqaaiabdYeamnaaDaaaleaacqGHRaWkaeaacqWGPbqAaaaabaGaemyAaKMaeyypa0JaeGymaedabaGaemOta4eaniabg+GivdGccqGH9aqpdaqeWbqaaKqbaoaalaaabaWaaabmaeaacqWGWbaCdaWgaaqaaiabdQgaQbqabaGaemitaW0aaWbaaeqabaGaemyAaKgaaiabcIcaOiabeY7aTnaaBaaabaGaemOAaOgabeaacqGGPaqkaeaacqWGQbGAcqGH9aqpcqaIXaqmaeaacqWGnbqtaiabggHiLdaabaGaeGymaeJaeyOeI0YaaabmaeaacqWGWbaCdaWgaaqaaiabdQgaQbqabaGaemitaW0aa0baaeaacqGHsislaeaacqWGPbqAaaGaeiikaGIaeqiVd02aaSbaaeaacqWGQbGAaeqaaiabcMcaPaqaaiabdQgaQjabg2da9iabigdaXaqaaiabd2eanbGaeyyeIuoaaaGccqGGUaGlaSqaaiabdMgaPjabg2da9iabigdaXaqaaiabd6eaobqdcqGHpis1aaaa@6736@

Here N is the total number of gene families and M is the number of rate categories. Analyses based on equation (2) as opposed to equation (1) revealed remarkably similar results and all conclusions made based on the old method remain qualitatively unchanged. The additional analyses and the altered tables are provided in Additional File 1 and also available at We thank Dr. Matt Spencer for pointing out the difference in averaging methods and thank Drs. David Bryant, Ofir Cohen, Miklós Csűrös, Tal Pupko, and Ed Susko for communication of ideas.



Authors’ Affiliations

Department of Biology, McMaster University


  1. Hao W, Golding GB: Uncovering rate variation of lateral gene transfer during bacterial genome evolution. BMC Genomics. 2008, 9: 235-10.1186/1471-2164-9-235.PubMedPubMed CentralView ArticleGoogle Scholar


© Hao and Golding; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.