Table 1 Selection of significant up-regulated expression of cytokines, cytokine receptors, chemokines, chemokine receptors, regulatory or protective genes after allogeneic transplantation compared to control group.
From: Activation of counter-regulatory mechanisms in a rat renal acute rejection model
Fold change | Probe set | Description | Gene symbol |
|---|---|---|---|
Cytokines | |||
121.2 | 1387711_at | interleukin 10 | Il10 |
84.1 | 1370790_at | interferon gamma | Ifng |
41.6 | 1391384_at | tumor necrosis factor (TNF superfamily, member 2) | Tnf |
15.4 | 1398256_at | interleukin 1 beta | Il1b |
13.1 | 1368592_at | interleukin 1 alpha | Il1a |
8.6 | 1369665_a_at | interleukin 18 | Il18 |
8.4 | 1368763_at | interleukin 3 | Il3 |
7.4 | 1369191_at | interleukin 6 | Il6 |
6.1 | 1369208_at | interleukin 7 | Il7 |
Cytokine receptors | |||
17 | 1389092_at | interleukin 2 receptor, gamma | Il2rg |
13.6 | 1387591_at | interleukin 2 receptor, alpha chain | Il2ra |
11.8 | 1369697_at | interleukin 8 receptor, beta | Il8rb |
10.1 | 1387394_at | interleukin 2 receptor, beta chain | Il2rb |
3.5 | 1370728_at | interleukin 13 receptor, alpha 1 | Il13ra1 |
3 | 1386987_at | interleukin 6 receptor | Il6r |
Chemokines | |||
139.7 | 1382454_at | chemokine (C-X-C motif) ligand 9 | Cxcl9 |
122.8 | 1387831_at | small inducible cytokine subfamily C, member 1 (lymphotactin) | Xcl1 |
39.3 | 1387969_at | chemokine (C-X-C motif) ligand 10 | Cxcl10 |
25.7 | 1391925_at | chemokine (C-C motif) ligand 19 (predicted) | Ccl19_predicted |
21.5 | 1369815_at | chemokine (C-C motif) ligand 3 | Ccl3 |
17.5 | 1367973_at | chemokine (C-C motif) ligand 2 | Ccl2 |
16.5 | 1379365_at | chemokine (C-X-C motif) ligand 11 | Cxcl11 |
15.2 | 1370832_at | small inducible cytokine A4 | Ccl4 |
6.7 | 1387316_at | chemokine (C-X-C motif) ligand 1 | Cxcl1 |
5.8 | 1369983_at | chemokine (C-C motif) ligand 5 | Ccl5 |
Chemokine receptors | |||
55.9 | 1369290_at | chemokine (C-C) receptor 5 | Ccr5 |
53.5 | 1370083_at | macrophage inflammatory protein-1 alpha receptor gene | Ccr1 |
45.9 | 1393929_at | chemokine (C-C motif) receptor 6 (predicted) | Ccr6_predicted |
41.1 | 1387742_at | chemokine (C-C motif) receptor 2 | Ccr2 |
11.2 | 1368192_at | chemokine (C-X-C motif) receptor 3 | Cxcr3 |
Regulatory or protective genes | |||
219.364 | 1369764_at | complement component 4 binding protein, alpha | C4bpa |
121.25 | 1387711_at | interleukin 10 | Il10 |
55.975 | 1368482_at | B-cell leukemia/lymphoma 2 related protein A1 | Bcl2a1 |
39.519 | 1371252_at | suppressor of cytokine signaling 1 | Socs1 |
39 | 1387835_at | interleukin 1 receptor antagonist | Il1rn |
36.72 | 1387608_at | indoleamine 2,3-dioxygenase | Indo |
28.885 | 1382622_at | cystatin F (leukocystatin) (predicted) | Cst7_predicted |
23.06 | 1370080_at | heme oxygenase (decycling) 1 | Hmox1 |
17.922 | 1370113_at | inhibitor of apoptosis protein 1 | Birc3 |
16.732 | 1368695_at | complement component 4 binding protein, beta | C4bpb |
8.305 | 1387638_a_at | cytotoxic T-lymphocyte-associated protein 4 | Ctla4 |
Immune cells related genes | |||
229.344 | 1385414_at | CD8 antigen, alpha chain | Cd8a |
144.253 | 1387378_at | ficolin B | Fcnb |
103.106 | 1370628_at | granzyme B | Gzmb |
67.326 | 1379293_at | granzyme A | Gzma |
35.114 | 1393917_at | CD163 antigen (predicted) | Cd163_predicted |
30.581 | 1387472_at | CD3 antigen delta polypeptide | Cd3d |
28.319 | 1387739_at | CD8 antigen, beta chain | Cd8b |
25 | 1370096_at | perforin 1 (pore forming protein) | Prf1 |
18.368 | 1370483_at | CD244 natural killer cell receptor 2B4 | Cd244 |