Table 2 Gene Ontology terms which are over- or under-represented among the rapidly or slowly evolving cichlid ORFs. Hypergeometic p-values are reported uncorrected for multiple testing. The number of ORFs of deviating evolutionary rate (#) relative to the number of core set ORFs (total) is given.
Representation | GO-ID | p-value | # | total | Description |
|---|---|---|---|---|---|
| Â | biological process | Â | 42 with higher p-distance (647 annotated) | ||
over | none | Â | Â | Â | Â |
under | GO:0050896 | 0.0161 | 1 | 86 | response to stimulus |
| Â | GO:0009987 | 0.0439 | 12 | 273 | cellular process |
| Â | molecular function | Â | 44 with higher p-distance (675 annotated) | ||
| Â | none | Â | Â | Â | Â |
| Â | Cellular component | Â | 40 with higher p-distance (619 annotated) | ||
over | GO:0015629 | 0.0327 | 6 | 39 | actin cytoskeleton |
under | none | Â | Â | Â | Â |
| Â | biological process | Â | 103 with lower p-distance (647 annotated) | ||
over | GO:0009987 | 0.0024 | 57 | 273 | cellular process |
over | GO:0007243 | 0.0052 | 8 | 19 | protein kinase cascade |
over | GO:0007155 | 0.0205 | 7 | 19 | cell adhesion |
over | GO:0040007 | 0.0208 | 6 | 15 | growth |
over | GO:0007154 | 0.0230 | 25 | 109 | cell communication |
over | GO:0007267 | 0.0071 | 7 | 16 | cell-cell signaling |
over | GO:0016477 | 0.0290 | 5 | 12 | cell migration |
over | GO:0040008 | 0.0290 | 5 | 12 | regulation of growth |
over | GO:0007409 | 0.0308 | 3 | 5 | axonogenesis |
over | GO:0007610 | 0.0308 | 3 | 5 | behavior |
over | GO:0015674 | 0.0308 | 3 | 5 | di-, tri-valent inorganic cation transport |
over | GO:0019752 | 0.0376 | 10 | 35 | carboxylic acid metabolic process |
over | GO:0007067 | 0.0402 | 4 | 9 | mitosis |
over | GO:0007417 | 0.0402 | 4 | 9 | central nervous system development |
under | GO:0008152 | 0.0016 | 63 | 477 | metabolic process |
under | GO:0046907 | 0.0180 | 2 | 44 | intracellular transport |
under | GO:0045045 | 0.0295 | 0 | 20 | secretory pathway |
under | GO:0009117 | 0.0421 | 0 | 18 | nucleotide metabolic process |
| Â | molecular function | Â | 110 with lower p-distance (675 annotated) | ||
over | GO:0004930 | 0.0157 | 4 | 7 | G-protein |
over | GO:0003774 | 0.0233 | 6 | 15 | motor activity |
over | GO:0005262 | 0.0264 | 2 | 2 | calcium channel |
over | GO:0008047 | 0.0324 | 6 | 16 | enzyme activator activity |
over | GO:0005509 | 0.0333 | 12 | 43 | calcium ion binding |
over | GO:0019899 | 0.0435 | 4 | 9 | enzyme binding |
under | GO:0005525 | 0.0116 | 1 | 36 | GTP binding |
under | GO:0005198 | 0.0407 | 8 | 85 | structural molecule activity |
under | GO:0051082 | 0.0467 | 0 | 17 | unfolded protein binding |
under | GO:0003743 | 0.0467 | 0 | 17 | translation initiation factor activity |
under | GO:0003924 | 0.0481 | 1 | 27 | GTPase activity |
under | GO:0003676 | 0.0483 | 17 | 147 | nucleic acid binding |
| Â | cellular component | Â | 97 with lower p-distance (619 annotated) | ||
over | GO:0016021 | 0.0096 | 22 | 88 | integral to membrane |
over | GO:0015630 | 0.0388 | 5 | 13 | microtubule cytoskeleton |
over | GO:0005625 | 0.0479 | 6 | 18 | soluble fraction |
over | GO:0005615 | 0.0479 | 6 | 18 | extracellular space |
under | GO:0032991 | 0.0001 | 19 | 222 | macromolecular complex |
under | GO:0043234 | 0.0015 | 18 | 195 | protein complex |
under | GO:0043226 | 0.0089 | 56 | 425 | organelle |
under | GO:0030529 | 0.0139 | 4 | 65 | ribonucleoprotein complex |
under | GO:0005829 | 0.0267 | 3 | 51 | cytosol |
under | GO:0005739 | 0.0311 | 6 | 75 | mitochondrion |