Figure 1

We built a one to one map between the human and mouse genomes from their WGA. (A) The track diagram shows TFos (unfilled features on outer tracks) and how they map to the other species (middle track). The thick part of the middle track is the mappable DNA. The features on the middle track can be mapped on the other species and are: SeqCons if not overlapping features from the other species (respective color), or FuncCons or FunctActive otherwise (green). The Venn diagrams use the same color code to show the amount (rounded to the closest Mb) of mappable material from one species to the other for DNA sequence, TFos, and DHS. For example, human TFos cover 121 Mb of the human genome. When mapped to mouse, these TFos cover 83 Mb of the mouse genome and 12 Mb of the sequence covered also by mouse TFos. The diagram for DHS is labeled in a similar fashion. (B) The distribution of mappable TFos nucleotides across cell types. The box-plot for each cell type summarizes the distribution of values for the fraction of nucleotides covered by TFos that can be mapped on the other species.