Figure 2
From: X-inactivation informs variance-based testing for X-linked association of a quantitative trait
Power improvement of weighted association test for the X chromosome (A) and the autosomes (B). For all SNPs with p-value below a nominal significance level (x-axis) in either the weighted test or the standard association test, the figure presents the fraction that have a more significant p-value in the former. Colors denote different traits. Fraction greater than 0.5 (dotted horizontal line) and its increase with significance level both point to higher power of the weighted association test over the standard test for chromosome X (A), while the trend is not obvious for the autosomes (B).