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Table 1 The Protobothrops elegans and P. flavoviridis transcriptomes are overwhelmingly dominated by PLA2s; however, the major PLA2s in each are pharmacologically very different. P. flavoviridis venom appears to be much more anti-coagulant, with coagulation Factor IX/X-binding proteins, and higher percentages of serine proteases, LAO, C-type lectins, 5′-nucleotidase, and phosphodiesterase [14]

From: Snake venoms are integrated systems, but abundant venom proteins evolve more rapidly

Transcript toxin class

Protobothrops elegans

Protobothrops flavoviridis

Phospholipase A2

77.1 %

55.5 %

Serine protease

10.4 %

11.8 %

Metalloprotease P-II

4.8 %

11.3 %

Metalloprotease P-III

3.2 %

6.0 %

BPP-CNP

1.4 %

2.6 %

Factor IX/X Activator A

 

2.4 %

Factor IX/X Activator B

 

1.2 %

LAO

0.5 %

3.1 %

VEGF

0.5 %

1.7 %

Phospholipase B

0.2 %

0.3 %

C-Type Lectin B

0.2 %

0.3 %

CRISP

0.1 %

2.0 %

5′-Nucleotidase

0.1 %

0.3 %

Nerve Growth Factor

0.1 %

0.1 %

Phosphodiesterase

0.1 %

0.2 %

Metalloprotease P-I

0.1 %

 

C-Type Lectin A

0.0 %

0.6 %

Galactose-binding Lectin

 

0.0 %

QC

0.0 %

0.1 %

Hyaluronidase

 

0.0 %

DPP-IV

0.0 %

0.0 %

APA

0.0 %

0.0 %