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Fig. 4 | BMC Genomics

Fig. 4

From: Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation

Fig. 4

NEUROD2 target genes are enriched in the subventricular-intermediate zone of the developing cortex. a Immunofluorescent staining against NEUROD2 and TBR1, and DAPI staining on coronal sections prepared from E14.5 mouse brain. NEUROD2 positive neurons are observed in the SVZ-IZ region of the developing cortex. Scale bar, 62 μm. b The percentage of overlap between NEUROD2 target genes and differentially expressed genes (DEGs) in the cortical plate (CP), subventricular zone/intermediate zone (SVZ-IZ), ventricular zone (VZ), and those that are preferentially expressed in two regions (CP∩SVZ-IZ and SVZ-IZ∩VZ) are plotted. NEUROD2 target genes (in blue) display an enrichment in DEGs of the different cortical regions (in particular the SVZ-IZ region) as compared to randomly selected genes (in red) from the mouse genome

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BMC Genomics

ISSN: 1471-2164

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