Fig. 4From: A nonsense mutation in B3GALNT2 is concordant with hydrocephalus in Friesian horsesRegional association plot of the region (on ECA1) most significantly associated with hydrocephalus in Friesian horses. Significance level based on genotype differences between cases (n = 13) and controls (n = 69) using a χ 2-test (2df). The horizontal line is the genome-wide Bonferroni corrected significance level (P = 1.68 × 10−6). Location of the B3GALNT2 gene [Ensembl:ENSECAG00000013338] is indicated by the black cross. SNPs surrounding B3GALNT2 are coloured in diminishing red to reflect LD (pair-wise r 2 values) between the candidate mutation in B3GALNT2 and SNPs. LD calculations between the mutation and the surrounding SNPs are based on genotypes for the mutation of 13 cases, 45 controls and 3 dams of cases and on SNP genotypes of all 13 cases and 69 controlsBack to article page