Fig. 2

Expression distribution for the mutated and unmutated IGHV samples with respect to the top 20 differentially expressed genes (total samples: 436). The y-axis represents relative expression (normalized sample values divided by the mean of each gene across all samples). The x-axis represents the IGVH status of the unmutated (yellow) and muted (green) patient groups. The boxplot bars indicate the lower and upper quartiles, the central bars indicate the mean, the whiskers indicate one standard deviation of the mean, and the box widths are proportional to the sample size. All genes were observed to be significantly different (p > 0.001)