Molecular alterations induced by a high-fat high-fiber diet in porcine adipose tissues: variations according to the anatomical fat location

Table 5 Most important genes participating to particularities in response to diet of perirenal adipose tissue

Gene symbol	Full name	Connectivity^a
IL10	Interleukin 10	205.8
C1QB	Complement component 1, q subcomponent, B chain	204.9
CYBB	Cytochrome b-245, beta polypeptide	201.9
C1QC	Complement component 1, q subcomponent, C chain	201.9
C1QA	Complement component 1, q subcomponent, A chain	199.2
ARRB2	Arrestin, beta 2	195.2
CYTH4	Cytohesin 4	194.8
CYBA	Cytochrome b-245, alpha polypeptide	194.7
NCKAP1L	NCK-associated protein 1-like	193.9
FCER1G	Fc fragment of IgE, high affinity I, receptor for gamma polypeptide	193.3
VAV1	Vav 1 guanine nucleotide exchange factor	192.9
FOLR1	Folate receptor 1	191.6
CD53	CD53 molecule	190.9
VSIG4	V-set and immunoglobulin domain containing 4	190.6
IL10RA	Interleukin 10 receptor, alpha	189.2
CFP	Complement factor properdin	188.8
VSIG4	V-set and immunoglobulin domain containing 4	188.2
CADM1	Cell adhesion molecule 1	188.1
NCF4	Neutrophil cytosolic factor 4, 40 kDa	187.8
F13A1	Coagulation factor XIII, A1 polypeptide	187.7

^aThe first 20 genes were ranked according to their connectivity value within the yellow module, which assembled a total of 411 unique genes in perirenal adipose tissue, all up-regulated by a high-fat high-fiber diet. The higher is the connectivity value, the stronger is the evidence that the gene is part of the module

ISSN: 1471-2164